Yay! Reports and videos are starting to come in!

So far, the best video I've seen of the panel is by Gonturan74. She has pretty good sound quality, and with just a few exceptions, she has the camera trained on Jared and Jensen regardless of who is actually talking. They have some priceless reactions.

Spoilerphobes, be warned! There is general discussion of season 4 plot points, as well as casting spoilers.

Jared was unusually quiet and seemed rather tired. Many fans have noticed that he often seems to protect Jensen a little by taking center stage away from his more reserved co-star and I thought it was interesting that in this panel Jensen seemed to step up to fulfill the same role for Jared. If Jared seemed unusually quiet and uncommunicative, Jensen seemed unusually talkative and relaxed. (And ready to throw the fangirls some bones - porn and assless chaps anyone?)

Unfortunately, I felt like a lot of the questions were kind of rehashes of things many fans already know - how the writer's strike affected season three, is Kripke really calling it quits after season five, etc. - but it was still an enjoyable panel, with some great moments, including the surprise appearance by the Ghostfacers and Jensen's instant transformation from Jensen Ackles to Dean Winchester.

For more updates, check out the Supernatural Wiki's Comic-Con 2008 page, which includes links to many more reports, videos, and other goodies.